BDNF/NT 3 Growth Factors Receptor (GP145 TrkB or Neurotrophic Tyrosine Kinase Receptor Type 2 or TrkB Tyrosine Kinase or Tropomyosin Related Kinase B or NTRK2 or EC 188.8.131.52) - BDNF/NT-3 growth factors receptor is a protein encoded by the NTRK2 gene. It is involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.
It acts as receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. It alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation.
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Top Companies mentioned
Addex Therapeutics Ltd
Boehringer Ingelheim GmbH
Chronos Therapeutics Ltd
Daiichi Sankyo Co Ltd
Loxo Oncology Inc
BDNF/NT 3 Growth Factors Receptor Industry Major Outlook
Pharmaceutical and Healthcare latest pipeline guide BDNF/NT 3 Growth Factors Receptor - Pipeline Review, H1 2018, provides comprehensive information on the therapeutics under development for BDNF/NT 3 Growth Factors Receptor, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.
It also reviews key players involved in BDNF/NT 3 Growth Factors Receptor (GP145 TrkB or Neurotrophic Tyrosine Kinase Receptor Type 2 or TrkB Tyrosine Kinase or Tropomyosin Related Kinase B or NTRK2 or EC 184.108.40.206) targeted therapeutics development with respective active and dormant or discontinued projects.
Currently, The molecules developed by companies in Pre-Registration, Phase III, Phase I, Preclinical and Discovery stages are 2, 1, 2, 7 and 4 respectively.
BDNF/NT 3 Growth Factors Receptor - Competitive Analysis
Key players are making innovative developments in BDNF/NT 3 Growth Factors Receptor industry. The same will help in improving the market performance. Heavy investments are made by major players in the R&D sector
The report provides a snapshot of the global therapeutic landscape for BDNF/NT 3 Growth Factors Receptor
The report reviews BDNF/NT 3 Growth Factors Receptor targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities.
The report reviews key players involved in BDNF/NT 3 Growth Factors Receptor targeted therapeutics and enlists all their major and minor projects.
The report assesses BDNF/NT 3 Growth Factors Receptor targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type.
The report summarizes all the dormant and discontinued pipeline projects.
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