A biologic material is a substance that actively alters the surrounding environment and effects a change in the environment that progresses through an active biological process, the effects can be seen through increased cellular activity, growth, and differentiation. A biologic material or bone graft attracts more cells to the fusion site can actively increase bone formation and stimulate spinal fusion. Spine Biologics constitute of material that can be used in bone fusion surgery, spinal cord injury and degenerative disc disease. The use of biologics in spine surgery has always been an important component in any spinal fusion surgery. The biologic material or bone graft is a critical element in the fusion healing process. In the past, there were few options, primarily using the patient's own bone (ie, autograft). The surgeon removed bone from one area of the patient's body (eg, iliac crest/hip) and used the bone as graft implanted into the spine for fusion. Many surgeons still use autograft as their primary bone graft of choice. However, the use of autograft often requires a separate surgical incision and removal of bone from an area of the body outside the spine, furthermore, availability of autograft is limited. Typically, bone can only be removed from an area once. This can present a problem for patients who require additional surgery. In children, the areas available for autograft are small, and there may not be enough bone to successfully heal the fusion. These scenarios represents some of the reasons why other types of biologic materials are needed. The ultimate goal of fusion is to restore disc height, alignment, and stability. In order for new bone to form, three critical elements are required:
osteoconductive scaffold (or a surface for bone to grow on, in, and through),
osteogenic cells (the cells that produce bone)
osteoinductive signals (proteins/molecules that tell the cells what to do)
Spine Biologics Market: Drivers & Restraints
Spine Biologics market is growing due to advancement in technology, demand for better minimally surgical procedures that support doctor and reduce in hospitalization timing. Also rise in prevalence of diseases due to aging population and related disease like rheumatoid and osteoarthritis, obesity, government funding, increased awareness and requirement for reduced hospital stay is driving the market in most regions. Spine Biologics has a tremendous demand in Americas region and pool the largest share in Spine Biologics market also due to increase in awareness Asia-Pacific region will show tremendous growth in future with highest population countries in Asia will drive it tremendously adding to the market share. The biggest restrain in the market is the healthcare cost for such procedures and the substitute product available.
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Spine Biologics Market: Segmentation
Spine Biologics can be segmented by product type as follows:
Demineralized Bone Matrix
Bone Morphogenetic Protein
Spine Biologics Market: Overview
Spine Biologics is gaining popularity as it is minimally invasive and require lesser time of stay at hospital than open surgical procedures. The market is experiencing increase owing to increased awareness and sophisticated diagnostic technique, also markets have been witnessing considerably high growth because of increase in patient pool and procedure numbers of osteoarthritis and rheumatoid arthritis. Spine Biologics market is experiencing growth in the developed countries because of high prevalence, improving healthcare facility, economic growth, insurance coverage and fast disease progression. North America constitutes the largest share in the global market, followed by Europe. The North American spine biologics market is experiencing significant growth in the region as a result of the growing population, awareness of newly developed technologies, increased per capita income of the hospitals and the people, improved medical literacy.
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Spine Biologics Market: Key Players
Some of the key market players in global Spine Biologics Market are Alphatech Spine, Medtronics, Biomet, Globus medical, Exactech, RTI Biologics, Zimmer, Small Bone Innovations, Stryker, Amedica, K2M, NuVasive, Precision Spine, TranS1 to name a few.
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