Monday, February 25th, 2013 - Taconic

Taconic to Distribute Yecuris Corporation Human Xenograft FRG(TM) KO Mouse Technologies in the US and Europe

HUDSON, NY and PORTLAND, OR--(Marketwire) - Taconic and Yecuris Corporation announce the formation of an exclusive marketing and distribution agreement to provide access to the Yecuris FRG(tm) KO animal portfolio. The agreement allows Taconic to promote and sell FRG(tm) primary cell xenograft animal models and HepaCur(tm) human primary hepatocytes developed by Yecuris Corporation for use in in vivo and in vitro applications.

"Taconic and Yecuris are coming together to provide the knowledge and materials necessary for scientists to increase human relevance in their drug and vaccine research by using models that contain human primary cells. Distribution of the animals and the education to use them is a critical step in the maturation of this field, which has been hindered by a lack of access. The combination of the two companies' portfolios of technologies represents a significant advance in the mainstreaming of these next generation models, and provides some insight into the future direction of scientific advances," said John Bial, president and chief executive officer of Yecuris. 

"Joining forces with Yecuris to provide ready access to their advanced technologies and products is Taconic's most recent step in building its portfolio of humanized model solutions," noted Todd Little, Taconic president and chief executive officer. "Taconic is strategically positioned to support our customers with the most relevant genetic and cellular humanized models for translational studies in oncology, metabolism, immunology and toxicity. Taconic now combines its expertise and experience in genetic humanized models with Yecuris' humanized liver models and human hepatocytes to provide our customers an even more complete solution for early stage drug development and testing."

Humanized animal models have been developed through genetic modification to provide specific attributes that are genetically human. The Taconic tADMET(tm) portfolio contains a unique collection of genetically humanized mouse models for genes involved in drug metabolism and disposition and allows for improved predictions of drug responses in humans. Yecuris technologies have been used to generate animals that allow the engraftment of human primary cells, specifically liver and immune, that replaces the native animal organ systems. The modified animals have a variety of human attributes passed on from the human cells, including human metabolism and toxicity profiles, and the ability to become infected with human pathogens and viruses like malaria and hepatitis. The combined marketing of both genetically and tissue humanized mouse models by Taconic provides seamless access to an unparalleled portfolio of translational mouse models, in vitro tools and related services.

Contact Profile


Taconic is a leading supplier of life sciences solutions to researchers throughout the world, offering innovative laboratory animal models and scientific services that facilitate in vivo studies and accelerate drug discovery. Taconic's wide range of advanced solutions include custom model design, generation and production, imaging, off-the shelf model repositories, compound profiling, contract research, contract breeding, genetic monitoring and health testing. Headquartered in New York's Hudson River Valley, Taconic operates seven breeding facilities and three service laboratories in the US and Europe, and maintains a staff of over 1,000 scientific specialists committed to technological innovation.
Susan Fogt
P: +1 518 697 3962

Yecuris Corporation

Yecuris Corporation is a Portland, Oregon based biotechnology company that develops animal xenograft technologies to support primary human cell and organ engraftment for use in drug discovery, toxicology, infectious disease, and cell therapy applications. Visit us at our website:
Dianne Danowski-Smith
P: 503.201.7019


Taconic and Yecuris Corporation , Strategic Marketing Alliance, Marketing



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